Article
Dendritic cells' characteristics in patients with treated systemic lupus erythematosus.
Acta biochimica Polonica - 30 Jul 2020
Wardowska Anna, Smoleńska Żaneta, Lisowska Katarzyna A, Zdrojewski Zbigniew, Pikuła Michał
Abstract excerpt
The systemic lupus erythematosus (SLE) is a chronic autoimmune disease related to a loss of immune tolerance against autoantigens that leads to tissue inflammation and organ dysfunction. Constant stimulation of dendritic cells (DC) with autoantigens is hypothesized to increase the B cells' activity which are involved in production of autoantibodies that play an essential role in the SLE development. We focused...
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