Article
The many layers of epigenetic dysfunction in B-cell lymphomas.
Current opinion in hematology - 1 Jul 2016
Jiang Yanwen, Dominguez Pilar M, Melnick Ari M
Abstract excerpt
PURPOSE OF REVIEW: Perturbation of the epigenome is emerging as a central driving force in the pathogenesis of diffuse large B-cell lymphomas (DLBCL) and follicular lymphoma. The purpose of this review is to explain how alteration of different layers of the epigenome contributes to the biology and clinical features of these tumors. RECENT FINDINGS: Key new findings implicate DNA methylation heterogeneity as a...
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