Article
Follicular lymphoma, a B cell malignancy addicted to epigenetic mutations.
Epigenetics - 4 May 2017
Korfi Koorosh, Ali Sara, Heward James A, Fitzgibbon Jude
Abstract excerpt
While follicular lymphoma (FL) is exquisitely responsive to immuno-chemotherapy, many patients follow a relapsing remitting clinical course driven in part by a common precursor cell (CPC) population. Advances in next generation sequencing have provided valuable insights into the genetic landscape of FL and its clonal evolution in response to therapy, implicating perturbations of epigenetic regulators as a...
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