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Article

Histone Modifications and Their Targeting in Lymphoid Malignancies

2021-11-17

Abstract excerpt

In a wide range of lymphoid neoplasms, the process of malignant transformation is associated to somatic mutations in B cells that affect the epigenetic machinery. Consequential alterations in histone modifications contribute to disease-specific changes in the transcriptional program. Affected genes commonly play important roles in cell cycle regulation, apoptosis-inducing signal transduction and DNA damage respons...

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Literature Corpus work
89e84c68-21b1-51a2-944c-127f0ffc8000
DOI
10.20944/preprints202111.0317.v1
Open publication

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Histone Modifications and Their Targeting in Lymphoid MalignanciesDOI 10.20944/preprints202111.0317.v1
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