Article
Mutation of chromatin modifiers; an emerging hallmark of germinal center B-cell lymphomas.
Blood cancer journal - 16 Oct 2015
Lunning M A, Green M R
Abstract excerpt
Subtypes of non-Hodgkin's lymphomas align with different stages of B-cell development. Germinal center B-cell (GCB)-like diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL) and Burkitt's lymphoma (BL) each share molecular similarities with normal GCB cells. Recent next-generation sequencing studies have gained insight into the genetic etiology of these malignancies and revealed a high frequency of...
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