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Article

Beyond genomics - Targeting the epigenome in diffuse large B-cell lymphoma.

Cancer treatment reviews - 1 Sept 2017

Kühnl Andrea, Cunningham David, Chau Ian

Abstract excerpt

After decades of intense research on genetic alterations in cancer and successful implementation of genetically-based targeted therapies, the field of cancer epigenetics is only beginning to be fully recognized. The discovery of frequent mutations in genes modifying the epigenome in diffuse large B-cell lymphoma (DLBCL) has highlighted the outstanding role of epigenetic deregulation in this disease....

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Epigenesis, Genetic
Forecasting
Genetic Therapy
Genomics
Lymphoma, Large B-Cell, Diffuse
Molecular Targeted Therapy

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Precision Medicine

Treatment Outcome

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PMID: 28822237
DOI: 10.1016/j.ctrv.2017.07.009

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