Article
Beyond genomics - Targeting the epigenome in diffuse large B-cell lymphoma.
Cancer treatment reviews - 1 Sept 2017
Kühnl Andrea, Cunningham David, Chau Ian
Abstract excerpt
After decades of intense research on genetic alterations in cancer and successful implementation of genetically-based targeted therapies, the field of cancer epigenetics is only beginning to be fully recognized. The discovery of frequent mutations in genes modifying the epigenome in diffuse large B-cell lymphoma (DLBCL) has highlighted the outstanding role of epigenetic deregulation in this disease....
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