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Article

Allelic Imbalance in Regulation of ANRIL through Chromatin Interaction at 9p21 Endometriosis Risk Locus.

PLoS genetics - 1 Apr 2016

Nakaoka Hirofumi, Gurumurthy Aishwarya, Hayano Takahide, Ahmadloo Somayeh, Omer Waleed H, Yoshihara Kosuke, Yamamoto Akihito, Kurose Keisuke, Enomoto Takayuki, Akira Shigeo, Hosomichi Kazuyoshi, Inoue Ituro

Abstract excerpt

Genome-wide association studies (GWASs) have discovered numerous single nucleotide polymorphisms (SNPs) associated with human complex disorders. However, functional characterization of the disease-associated SNPs remains a formidable challenge. Here we explored regulatory mechanism of a SNP on chromosome 9p21 associated with endometriosis by leveraging "allele-specific" functional genomic approaches. By...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27055116
DOI: 10.1371/journal.pgen.1005893
PMCID: PMC4824487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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