Article
Imputing Gene Expression in Uncollected Tissues Within and Beyond GTEx.
American journal of human genetics - 7 Apr 2016
Wang Jiebiao, Gamazon Eric R, Pierce Brandon L, Stranger Barbara E, Im Hae Kyung, Gibbons Robert D, Cox Nancy J, Nicolae Dan L, Chen Lin S
Abstract excerpt
Gene expression and its regulation can vary substantially across tissue types. In order to generate knowledge about gene expression in human tissues, the Genotype-Tissue Expression (GTEx) program has collected transcriptome data in a wide variety of tissue types from post-mortem donors. However, many tissue types are difficult to access and are not collected in every GTEx individual. Furthermore, in non-GTEx...
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