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GROMTools: scalable individual-level GReX imputation for mega-biobank-scale cohorts

2026-04-28

Abstract excerpt

<h4>Motivation</h4> The computational burden of individual-level genetically regulated gene expression (GReX) imputation has risen sharply with the growth of human mega-biobanks and the rapid expansion of transcriptomic imputation models across tissues and single-cell hierarchies. Existing tools were not designed for this setting and require complex, memory-intensive workflows that are poorly matched to shared an...

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Literature Corpus work
f20f7fbc-3c73-5f2f-8d63-9bde0057073c
DOI
10.64898/2026.04.27.26351635
Open publication

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GROMTools: scalable individual-level GReX imputation for mega-biobank-scale cohortsDOI 10.64898/2026.04.27.26351635
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