Article
Sulforaphane regulates phenotypic and functional switching of both induced and spontaneously differentiating human monocytes.
International immunopharmacology - 1 Jun 2016
Pal Sanjima, Konkimalla V Badireenath
Abstract excerpt
At the site of inflammation, switching default on polarization of monocyte differentiation into classically activated macrophages (M1 type) is one of the pathogenic outcomes in several inflammatory autoimmune diseases, such as rheumatoid arthritis and osteoarthritis. In rheumatoid and osteoarthritis, a soluble collagen known as self-antigen is considered as a biomarker and acts as an important inflammatory...
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