Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL‐8 induces miR‐424‐5p expression and modulates SOCS2/STAT5 signaling pathway in oral squamous cell carcinoma

22 Mar 2016

Abstract excerpt

Suppressor of cytokine signaling (SOCS) proteins are negative feedback regulators of the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway. Dysregulation of SOCS protein expression in cancers can be one of the mechanisms that maintain STAT activation, but this mechanism is still poorly understood in oral squamous cell carcinoma (OSCC). Here, we report that SOCS2 protein is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Cytokine Signaling Pathways and Interactions
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27038552
DOI: 10.1016/j.molonc.2016.03.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL‐8 induces miR‐424‐5p expression and modulates SOCS2/STAT5 signaling pathway in oral squamous cell carcinomaPMID 27038552Read ↗

Emerging roles of suppressor of cytokine signaling 3 in human cancersSemantic proximity Read ↗

MiR-142-3p Suppresses SOCS6 Expression and Promotes Cell Proliferation in Nasopharyngeal CarcinomaSemantic proximity Read ↗

SOCS, inflammation, and cancerSemantic proximity Read ↗

Role of SOCS1 in tumor progression and therapeutic applicationSemantic proximity Read ↗

Japanese Encephalitis Virus exploits the microRNA-432 to regulate the expression of Suppressor of Cytokine Signaling (SOCS) 5Semantic proximity Read ↗

Suppressors of Cytokine Signaling (SOCS) Proteins and JAK/STAT PathwaysSemantic proximity Read ↗

Altered expression of SOCS genes periodontitisSemantic proximity Read ↗

SOCS2 physiological and pathological functionsSemantic proximity Read ↗

SOCS2: physiological and pathological functions.Semantic proximity Read ↗

miR-196b is a prognostic factor of human laryngeal squamous cell carcinoma and promotes tumor progression by targeting SOCS2Semantic proximity Read ↗

miR‐4458 regulates cell proliferation and apoptosis through targeting SOCS1 in triple‐negative breast cancerSemantic proximity Read ↗

IL-22 promotes the progression of breast cancer through regulating HOXB-AS5Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.