Altered expression of SOCS genes periodontitis

Abstract excerpt

Suppressor of cytokine signalling (SOCS) family comprises a group of proteins that impede JAK/STAT signalling, thus being involved in the pathogenesis of immune-related conditions. In the present work, we aimed at identification of the role of SOCS genes in the pathogenesis of periodontitis through evaluation of their expression levels both in the circulation and in the affected tissues of patients. Thus, we...

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• Cytokine Signaling Pathways and Interactions
• Inflammatory mediators and NSAID effects
• NF-κB Signaling Pathways