Article
Identification of genetic variation in the swine toll-like receptors and development of a porcine TLR genotyping array.
Genetics, selection, evolution : GSE - 31 Mar 2016
Clop Alex, Huisman Abe, van As Pieter, Sharaf Abdoallah, Derdak Sophia, Sanchez Armand
Abstract excerpt
BACKGROUND: Toll-like receptors (TLR) are crucial in innate immunity for the recognition of a broad range of microbial pathogens and are expressed in multiple cell types. There are 10 TLR genes described in the pig genome. RESULTS: With a twofold objective i.e. to catalogue genetic variants in porcine TLR genes and develop a genotyping array for genetic association studies on immune-related traits, we combined...
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