Article
Biased distribution of single nucleotide polymorphisms (SNPs) in porcine Toll-like receptor 1 (TLR1), TLR2, TLR4, TLR5, and TLR6 genes.
Immunogenetics - 1 May 2006
Shinkai Hiroki, Tanaka Maiko, Morozumi Takeya, Eguchi-Ogawa Tomoko, Okumura Naohiko, Muneta Yoshihiro, Awata Takashi, Uenishi Hirohide
Abstract excerpt
Toll-like receptors (TLRs) recognize various microbial components and induce immune responses. Polymorphisms in TLRs may influence their recognition of pathogen-derived molecules; swine TLRs are predicted to be associated with responses to infectious diseases such as pneumonia. In this study, we searched for single nucleotide polymorphisms (SNPs) in the coding sequences of porcine TLR1, TLR2, TLR4, TLR5, and TLR6...
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