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Article

Toll-like receptor 4 genetic diversity among pig populations.

Animal genetics - 1 Jun 2009

Palermo S, Capra E, Torremorell M, Dolzan M, Davoli R, Haley C S, Giuffra E

Abstract excerpt

The transmembrane glycoprotein encoded by the Toll-like receptor 4 gene (TLR4) acts as the transducing subunit of the lipopolysaccharide receptor complex of mammals, which is a major sensor of infections by Gram-negative bacteria. As variation in TLR4 may alter host immune response to lipopolysaccharide, the association between TLR4 polymorphisms and immune traits of the respiratory and gut systems has important...

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Identifiers

PMID: 19290993
DOI: 10.1111/j.1365-2052.2008.01833.x

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TLR4

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