Article
TLR4 single nucleotide polymorphisms (SNPs) associated with Salmonella shedding in pigs.
Journal of applied genetics - 1 May 2014
Kich Jalusa Deon, Uthe Jolita Janutenaite, Benavides Magda Vieira, Cantão Maurício Egídio, Zanella Ricardo, Tuggle Christopher Keith, Bearson Shawn Michelle Dunkin
Abstract excerpt
Toll-like receptor 4 (TLR4) is a key factor in the innate immune recognition of lipopolysaccharide (LPS) from Gram-negative bacteria. Previous studies from our group identified differences in the expression profile of TLR4 and genes affected by the TLR4 signaling pathway among pigs that shed varying levels of Salmonella, a Gram-negative bacterium. Therefore, genetic variation in this gene may be involved with the...
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