Identification of Nonsynonymous SNPs in Immune-Related Genes Associated with Pneumonia Severity in Pigs.

doi:10.3390/genes15081103

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Article

Identification of Nonsynonymous SNPs in Immune-Related Genes Associated with Pneumonia Severity in Pigs.

Genes - 21 Aug 2024

Shinkai Hiroki, Suzuki Kasumi, Itoh Tomohito, Yoshioka Gou, Takenouchi Takato, Kitazawa Haruki, Uenishi Hirohide

Abstract excerpt

We previously showed that several polymorphisms in genes encoding pattern recognition receptors that cause amino acid substitutions alter pathogen recognition ability and disease susceptibility in pigs. In this study, we expanded our analysis to a wide range of immune-related genes and investigated polymorphism distribution and its influence on pneumonia in multiple commercial pig populations. Among the...

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PMID: 39202462
DOI: 10.3390/genes15081103
PMCID: PMC11353625

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