Circulating tumor DNA and circulating tumor cells in metastatic triple negative breast cancer patients.

doi:10.1002/ijc.29265

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Article

Circulating tumor DNA and circulating tumor cells in metastatic triple negative breast cancer patients.

International journal of cancer - 1 May 2015

Madic Jordan, Kiialainen Anna, Bidard Francois-Clement, Birzele Fabian, Ramey Guillemette, Leroy Quentin, Rio Frio Thomas, Vaucher Isabelle, Raynal Virginie, Bernard Virginie, Lermine Alban, Clausen Inga, Giroud Nicolas, Schmucki Roland, Milder Maud, Horn Carsten, Spleiss Olivia, Lantz Olivier, Stern Marc-Henri, Pierga Jean-Yves, Weisser Martin, Lebofsky Ronald

Abstract excerpt

Circulating tumor DNA (ctDNA) is a new circulating tumor biomarker which might be used as a prognostic biomarker in a way similar to circulating tumor cells (CTCs). Here, we used the high prevalence of TP53 mutations in triple negative breast cancer (TNBC) to compare ctDNA and CTC detection rates and prognostic value in metastatic TNBC patients. Forty patients were enrolled before starting a new line of...

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Identifiers

PMID: 25307450
DOI: 10.1002/ijc.29265

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