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Article

Evaluation and consequences of heterogeneity in the circulating tumor cell compartment.

Oncotarget - 26 Jul 2016

Brouwer Anja, De Laere Bram, Peeters Dieter, Peeters Marc, Salgado Roberto, Dirix Luc, Van Laere Steven

Abstract excerpt

A growing understanding of the molecular biology of cancer and the identification of specific aberrations driving cancer evolution have led to the development of various targeted agents. Therapeutic decisions concerning these drugs are often guided by single biopsies of the primary tumor. Yet, it is well known that tumors can exhibit significant heterogeneity and change over time as a result of selective...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26980749
DOI: 10.18632/oncotarget.8015
PMCID: PMC5217044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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