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Article

Heterozygous caveolin-3 mice show increased susceptibility to palmitate-induced insulin resistance.

Physiological reports - 1 Mar 2016

Talukder M A Hassan, Preda Marilena, Ryzhova Larisa, Prudovsky Igor, Pinz Ilka M

Abstract excerpt

Insulin resistance and diabetes are comorbidities of obesity and affect one in 10 adults in the United States. Despite the high prevalence, the mechanisms of cardiac insulin resistance in obesity are still unclear. We test the hypothesis that the insulin receptor localizes to caveolae and is regulated through binding to caveolin-3 (CAV3). We further test whether haploinsufficiency forCAV3 increases the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diet, High-Fat

Share to Glucose Intolerance

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Source

Open in PubMed Open full text

Identifiers

PMID: 27033451
DOI: 10.14814/phy2.12736
PMCID: PMC4814890

Genes

CAV3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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