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Article

Functional analysis of 'a' determinant mutations associated with occult HBV in HIV-positive South Africans.

The Journal of general virology - 1 Jul 2016

Powell Eleanor A, Boyce Ceejay L, Gededzha Maemu P, Selabe Selokela G, Mphahlele M Jeffrey, Blackard Jason T

Abstract excerpt

Occult hepatitis B is defined by the presence of hepatitis B virus (HBV) DNA in the absence of hepatitis B surface antigen (HBsAg). Occult HBV is associated with the development of hepatocellular carcinoma, reactivation during immune suppression, and virus transmission. Viral mutations contribute significantly to the occult HBV phenotype. Mutations in the 'a' determinant of HBsAg are of particular interest, as...

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Share to Carcinoma, Hepatocellular
Share to Enzyme-Linked Immunosorbent Assay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B, Chronic

Share to Hepatitis B Surface Antigens

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Source

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Identifiers

PMID: 27031988
DOI: 10.1099/jgv.0.000469
PMCID: PMC5756483

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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