Article
Molecular and functional analysis of occult hepatitis B virus isolates from patients with hepatocellular carcinoma.
Hepatology (Baltimore, Md.) - 1 Feb 2007
Pollicino Teresa, Raffa Giuseppina, Costantino Lucy, Lisa Antonella, Campello Cesare, Squadrito Giovanni, Levrero Massimo, Raimondo Giovanni
Abstract excerpt
UNLABELLED: Occult HBV infection is characterized by the persistence of HBV DNA in the liver of individuals negative for HBV surface antigen (HBsAg). Occult HBV may exist in the hepatocytes as a free genome, although the factors responsible for the very low viral replication and gene expression usually observed in this peculiar kind of infection are mostly unknown. Aims of this study were to investigate whether...
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