Article
Plasma levels of TGF-β1 in homeostasis of the inflammation in sickle cell disease.
Cytokine - 1 Apr 2016
Torres Lidiane de Souza, Okumura Jéssika Viviani, da Silva Danilo Grünig Humberto, Belini Júnior Édis, de Oliveira Renan Garcia, Mimura Kallyne Kioko Oliveira, Lobo Clarisse Lopes de Castro, Oliani Sonia Maria, Bonini Domingos Claudia Regina
Abstract excerpt
Sickle cell disease (SCD) represents a chronic inflammatory condition with complications triggered by the polymerization of hemoglobin S (Hb S), resulting in a series of cellular interactions mediated by inflammatory cytokines, as the transforming growth factor beta (TGF-β), which plays an important role in inflammation resolution. This study assessed the relation between SCD inflammation and the plasma...
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