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Article

Phospholipase A2 Receptor Gene Polymorphisms Alter its Functions and Present a Genetic Risk of an Increased Intima-Media Thickness of the Carotid Artery.

Journal of atherosclerosis and thrombosis - 1 Oct 2016

Si Nguyen Van, Fujioka Daisuke, Watanabe Kazuhiro, Watanabe Yosuke, Watanabe Kazunori, Nakamura Kazuto, Yamaguchi Kazuyuki, Uematsu Manabu, Kugiyama Kiyotaka

Abstract excerpt

AIMS: Phospholipase A2 receptor 1 (PLA2R) has multiple biological functions other than functioning as a receptor for secretory PLA2s. Two nonsynonymous polymorphisms in the C-type lectin-like domains (CTLD) 1 of PLA2R gene have been associated with idiopathic membranous nephropathy. This study examined whether the same PLA2R polymorphisms may alter functions of PLA2R in cells expressing the variant PLA2R. In...

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Identifiers

PMID: 27025682
DOI: 10.5551/jat.34330
PMCID: PMC5098923

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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