Article
Single nucleotide polymorphisms in the phospholipase A2 receptor gene are associated with genetic susceptibility to idiopathic membranous nephropathy.
Nephron. Clinical practice - 1 Jan 2011
Kim Sejoong, Chin Ho Jun, Na Ki Young, Kim Suhnggwon, Oh Jieun, Chung Wookyung, Noh Jung Woo, Lee Young Ki, Cho Jong Tae, Lee Eun Kyoung, Chae Dong-Wan
Abstract excerpt
BACKGROUND: The phospholipase A(2) receptor (PLA2R) is a major antigen found in patients with idiopathic membranous nephropathy (MN). The relationship of genetic polymorphisms of PLA2R with the susceptibility and clinical outcomes of this disease is unknown. METHODS: We studied 199 patients with idiopathic MN followed up for 3.7 ± 3.2 years. We enrolled 33 patients with secondary MN and 356 subjects with normal...
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