Article
APOL1 risk variants and kidney disease: what we know so far.
Jornal brasileiro de nefrologia - 1 Jan 2000
Siemens Tobias August, Riella Miguel Carlos, Moraes Thyago Proença de, Riella Cristian Vidal
Abstract excerpt
There are striking differences in chronic kidney disease between Caucasians and African descendants. It was widely accepted that this occurred due to socioeconomic factors, but recent studies show that apolipoprotein L-1 (APOL1) gene variants are strongly associated with focal segmental glomerulosclerosis, HIV-associated nephropathy, hypertensive nephrosclerosis, and lupus nephritis in the African American...
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