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Mitochondrial Stat3, the Need for Design Thinking

1 Jan 2016

Abstract excerpt

Stat3 has been studied extensively as a transcription factor, however the finding that Stat3 also localizes to mitochondria has opened a new area to discover non-classical functions. Here we review the current knowledge of mitochondrial Stat3 as a regulator of the electron transport chain (ETC) and its impact on mitochondrial production of ATP and ROS. We also describe recent findings identifying Stat3 as a...

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PMID: 27019635
DOI: 10.7150/ijbs.15153

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