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Article

Stat3

3 Sept 2014

Abstract excerpt

Chronic inflammation predisposes tissue to cancer development. Individuals afflicted with inflammatory bowel diseases are at an increased risk of developing colorectal cancer depending on disease severity, duration, and management. The intestinal epithelium exhibits mitochondrial dysfunction during colitis and colitis-associated cancer. Signal Transducer and Activator of Transcription (Stat)-3 is a transcription...

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Identifiers

PMID: 25185686
DOI: 10.1097/mib.0000000000000180

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