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Article

STAT3 and metabolism: How many ways to use a single molecule?

5 Feb 2014

Abstract excerpt

The transcription factor Signal Transducer and Activator of Transcription (STAT)3 has been considered as a potential anticancer target since its first description as an oncogene in 1999, recently leading to STAT3 inhibitors been brought to clinical trial for the treatment of solid tumors. However, the past 14 years of intense basic research have uncovered novel STAT3-mediated pathways that could affect the...

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PMID: 24500994
DOI: 10.1002/ijc.28767

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