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Article

The mutational repertoire of uterine sarcomas and carcinosarcomas in a Brazilian cohort: A preliminary study.

Clinics (Sao Paulo, Brazil) - 1 Jan 2021

da Costa Leonardo Tomiatti, Dos Anjos Laura Gonzalez, Kagohara Luciane Tsukamoto, Torrezan Giovana Tardin, De Paula Claudia A Andrade, Baracat Edmund Chada, Carraro Dirce Maria, Carvalho Katia Candido

Abstract excerpt

OBJECTIVES: The present study aimed to contribute to the catalog of genetic mutations involved in the carcinogenic processes of uterine sarcomas (USs) and carcinosarcomas (UCSs), which may assist in the accurate diagnosis of, and selection of treatment regimens for, these conditions. METHODS: We performed gene-targeted next-generation sequencing (NGS) of 409 cancer-related genes in 15 US (7 uterine leiomyosarcoma...

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Brazil
Carcinosarcoma
Mutation
Sarcoma
Uterine Neoplasms

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PMID: 33503190
DOI: 10.6061/clinics/2021/e2324
PMCID: PMC7798418

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