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Article

Kinetic Measurements Reveal Enhanced Protein-Protein Interactions at Intercellular Junctions.

Scientific reports - 24 Mar 2016

Shashikanth Nitesh, Kisting Meridith A, Leckband Deborah E

Abstract excerpt

The binding properties of adhesion proteins are typically quantified from measurements with soluble fragments, under conditions that differ radically from the confined microenvironment of membrane bound proteins in adhesion zones. Using classical cadherin as a model adhesion protein, we tested the postulate that confinement within quasi two-dimensional intercellular gaps exposes weak protein interactions that are...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27009566
DOI: 10.1038/srep23623
PMCID: PMC4806357

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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