Article
Genomically Driven Tumors and Actionability across Histologies: BRAF-Mutant Cancers as a Paradigm.
Molecular cancer therapeutics - 1 Apr 2016
Turski Michelle L, Vidwans Smruti J, Janku Filip, Garrido-Laguna Ignacio, Munoz Javier, Schwab Richard, Subbiah Vivek, Rodon Jordi, Kurzrock Razelle
Abstract excerpt
The diagnosis, classification, and management of cancer are traditionally dictated by the site of tumor origin, for example, breast or lung, and by specific histologic subtypes of site-of-origin cancers (e.g., non-small cell versus small cell lung cancer). However, with the advent of sequencing technologies allowing for rapid, low cost, and accurate sequencing of clinical samples, new observations suggest an...
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