Article
The molecular pathology of cancer.
Nature reviews. Clinical oncology - 1 May 2010
Harris Timothy J R, McCormick Frank
Abstract excerpt
Rapid technical advances in DNA sequencing and genome-wide association studies are driving the discovery of the germline and somatic mutations that are present in different cancers. Mutations in genes involved in cellular signaling are common, and often shared by tumors that arise in distinct anatomical locations. Here we review the most important molecular changes in different cancers from the perspective of...
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