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Article

The Brd4 acetyllysine-binding protein is involved in activation of polyomavirus JC.

Journal of neurovirology - 1 Oct 2016

Wollebo Hassen S, Bellizzi Anna, Cossari Dominique H, Salkind Julian, Safak Mahmut, White Martyn K

Abstract excerpt

Brd4 is an epigenetic reader protein and a member of the BET (bromodomain and extra terminal domain) family of proteins with two bromodomains that recognize acetylated lysine residues. Brd4 specifically binds to acetylated transcription factor NF-κB p65 and coactivates transcription. Polyomavirus JC (JCV) is regulated by a noncoding control region (NCCR) containing promoter/enhancer elements for viral gene...

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Source

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Identifiers

PMID: 27007123
DOI: 10.1007/s13365-016-0435-6
PMCID: PMC5035168

Genes

PML
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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