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Article

Rad51 activates polyomavirus JC early transcription.

PloS one - 1 Jan 2014

White Martyn K, Kaminski Rafal, Khalili Kamel, Wollebo Hassen S

Abstract excerpt

The human neurotropic polyomavirus JC (JCV) causes the fatal CNS demyelinating disease progressive multifocal leukoencephalopathy (PML). JCV infection is very common and after primary infection, the virus is able to persist in an asymptomatic state. Rarely, and usually only under conditions of immune impairment, JCV re-emerges to actively replicate in the astrocytes and oligodendrocytes of the brain causing PML....

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Source

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Identifiers

PMID: 25310191
DOI: 10.1371/journal.pone.0110122
PMCID: PMC4195707

Genes

PML
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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