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Article

Epigenetic regulation of polyomavirus JC

23 Aug 2013

Abstract excerpt

BACKGROUND: Polyomavirus JC (JCV) causes the CNS demyelinating disease progressive multifocal leukoencephalopathy (PML), which occurs almost exclusively in people with immune deficiencies, such as HIV-1/AIDS patients. JCV infection is very common and usually occurs early in life. After primary infection, virus is controlled by the immune system but, rarely when immune function is impaired, it can re-emerge and...

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PMID: 23971673
DOI: 10.1186/1743-422x-10-264

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