Article
Analysis of the structure and function of EMRE in a yeast expression system.
Biochimica et biophysica acta - 1 Jun 2016
Yamamoto Takenori, Yamagoshi Ryohei, Harada Kazuki, Kawano Mayu, Minami Naoki, Ido Yusuke, Kuwahara Kana, Fujita Atsushi, Ozono Mizune, Watanabe Akira, Yamada Akiko, Terada Hiroshi, Shinohara Yasuo
Abstract excerpt
The mitochondrial calcium uniporter (MCU) complex is a highly-selective calcium channel, and this complex is believed to consist of a pore-forming subunit, MCU, and its regulatory subunits. As yeast cells lack orthologues of the mammalian proteins, the yeast expression system for the mammalian calcium uniporter subunits is useful for investigating their functions. We here established a yeast expression system for...
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