Article
CsoR Is Essential for Maintaining Copper Homeostasis in Mycobacterium tuberculosis.
PloS one - 1 Jan 2016
Marcus Sarah A, Sidiropoulos Sarah W, Steinberg Howard, Talaat Adel M
Abstract excerpt
Mycobacterium tuberculosis, a pathogen infecting one third of the world population, faces numerous challenges within the host, including high levels of copper. We have previously shown that M. tuberculosis CsoR is a copper inducible transcriptional regulator. Here we examined the hypothesis that csoR is necessary for maintaining copper homeostasis and surviving under various stress conditions. With an unmarked...
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