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Article

A novel copper‐responsive regulon in Mycobacterium tuberculosis

29 Oct 2010

Abstract excerpt

In this work we describe the identification of a copper-inducible regulon in Mycobacterium tuberculosis (Mtb). Among the regulated genes was Rv0190/MT0200, a paralogue of the copper metalloregulatory repressor CsoR. The five-locus regulon, which includes a gene that encodes the copper-protective metallothionein MymT, was highly induced in wild-type Mtb treated with copper, and highly expressed in an Rv0190/MT0200...

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PMID: 21166899
DOI: 10.1111/j.1365-2958.2010.07431.x

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