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Mycobacterium tuberculosis and Copper: A Newly Appreciated Defense against an Old Foe?

10 Jun 2015

Abstract excerpt

Several independent studies have recently converged upon the conclusion that the human bacterial pathogen Mycobacterium tuberculosis encounters copper during infections. At least three independently regulated pathways respond to excess copper and are required for the full virulence of M. tuberculosis in animals. In this review, I will discuss the functions of the best-characterized copper-responsive proteins in...

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PMID: 26055711
DOI: 10.1074/jbc.r115.640193

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