Article
DISC1 as a Possible Genetic Contribution to Opioid Dependence in a Polish Sample.
Journal of studies on alcohol and drugs - 1 Mar 2016
Fudalej Sylwia, Jakubczyk Andrzej, Kopera Maciej, Piwonski Jerzy, Bielecki Wojciech, Drygas Wojciech, Wasilewska Krystyna, Ilgen Mark, Bohnert Amy, Barry Kristen, Płoski Rafał, Blow Frederic C, Wojnar Marcin
Abstract excerpt
OBJECTIVE: Disrupted-in-schizophrenia 1 (DISC1) has been linked to vulnerability to a variety of psychiatric disorders and neuropsychiatric phenotypes. However, DISC1 has not been frequently examined as a potential risk factor for substance dependence. An association between opioid dependence and DISC1 rs2738888 polymorphism has been recently reported. In addition, opioid dependence was associated with rs6419156...
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