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Article

Phosphorylation of eIF2α on Threonine 169 is not required for Trypanosoma brucei cell cycle arrest during differentiation.

Molecular and biochemical parasitology - 1 Jan 2000

Avila Carla Cristi D C, Peacock Lori, Machado Fabricio Castro, Gibson Wendy, Schenkman Sergio, Carrington Mark, Castilho Beatriz A

Abstract excerpt

The trypanosome life cycle consists of a series of developmental forms each adapted to an environment in the relevant insect and/or mammalian host. The differentiation process from the mammalian bloodstream form to the insect-midgut procyclic form in Trypanosoma brucei occurs in two steps in vivo. First proliferating 'slender' bloodstream forms differentiate to non-dividing 'stumpy' forms arrested in G1. Second,...

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Identifiers

PMID: 26996431
DOI: 10.1016/j.molbiopara.2016.03.004
PMCID: PMC4850487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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