Article
Genetics polymorphism in DNA repair genes by base excision repair pathway (XRCC1) and homologous recombination (XRCC2 and RAD51) and the risk of breast carcinoma in the Polish population.
Polish journal of pathology : official journal of the Polish Society of Pathologists - 1 Jan 2010
Romanowicz Hanna, Smolarz Beata, Baszczyński Jakub, Zadrożny Marek, Kulig Andrzej
Abstract excerpt
Background : Several polymorphisms in the DNA repair gene have been extensively studied in the association with various human cancers such as breast cancer. Material and methods : We investigated the association of polymorphisms in the DNA repair genes XRCC1-Arg399Gln, XRCC2-Arg188His and RAD51-135G/C with the breast cancer risk. Genotypes were determined by PCR-RFLP assays in 220 patients with breast cancer and...
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