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Polymorphisms of the XRCC1 gene and breast cancer risk in the Mexican population.

Familial cancer - 1 Sept 2015

Macías-Gómez Nelly M, Peralta-Leal Valeria, Meza-Espinoza Juan Pablo, Gutiérrez-Angulo Melva, Durán-González Jorge, Ramírez-González Juan Manuel, Gaspar-Del Toro Alejandra, Norberto-Rodríguez Adolfo, Leal-Ugarte Evelia

Abstract excerpt

The purpose of this case-control study was to evaluate the association of XRCC1 Arg194Trp and Arg399Gln polymorphisms with susceptibility to breast cancer (BC) in a Mexican population. We analysed DNA samples from 345 BC patients and 352 control subjects by polymerase chain reaction-restriction fragment length polymorphism. The frequency of the 399Gln allele was 23% in controls and 29% in patients [OR 1.38...

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Source

Identifiers

PMID: 25690738
DOI: 10.1007/s10689-015-9787-y

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Polymorphisms of the XRCC1 gene and breast cancer risk in the Mexican population.PMID 25690738Read ↗

Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241Met) polymorphisms with the risk of breast cancer: a case-control study in Egypt.Semantic proximity Read ↗

XRCC1 gene polymorphisms and breast cancer risk in different populations: a meta-analysis.Semantic proximity Read ↗

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XRCC1 Arg399Gln, Arg194Trp and Arg280His polymorphisms in breast cancer risk: a meta-analysis.Semantic proximity Read ↗

Impact of XRCC1 genetic variants on its tissue expression and breast cancer risk: A case-control study.Semantic proximity Read ↗

XRCC1 Arg399Gln gene polymorphism and breast cancer risk: a meta-analysis based on case-control studies.Semantic proximity Read ↗

Genetic polymorphisms of XRCC1 (codon 399) and susceptibility to breast cancer in Iranian women, a case-control study.Semantic proximity Read ↗

Association of the Arg194Trp and the Arg399Gln polymorphisms of the XRCC1 gene with risk occurrence and the response to adjuvant therapy among Polish women with breast cancer.Semantic proximity Read ↗

A prospective study of XRCC1 (X-ray cross-complementing group 1) polymorphisms and breast cancer risk.Semantic proximity Read ↗

A population-based case-control study of the Arg399Gln polymorphism in DNA repair gene XRCC1 and risk of breast cancer.Semantic proximity Read ↗

Polymorphism of XRCC1 (at codon 399) and susceptibility to breast cancer, a meta-analysis of the literatures.Semantic proximity Read ↗

[Relationship between polymorphisms of X-ray repair cross-complementing group 1 gene Arg194Trp, Arg399Gln and susceptibility of breast cancer].Semantic proximity Read ↗

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