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Article

Novel interferonopathies associated with mutations in RIG-I like receptors.

Cytokine & growth factor reviews - 1 Jun 2016

Buers Insa, Nitschke Yvonne, Rutsch Frank

Abstract excerpt

Type I interferonopathies are a relatively new class of inherited autoimmune disorders associated with an inborn elevated interferon response. Activation of cytosolic receptors which recognize viral double stranded RNA including the RIG-I (retinoic acid-inducible gene I) like receptors RIG-I and MDA5 (melanoma differentiation-associated gene 5) has been shown to induce the transcription of type I interferon...

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Share to Autoimmune Diseases
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Source

Identifiers

PMID: 26993858
DOI: 10.1016/j.cytogfr.2016.03.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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