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Targeting Type II Toxin–Antitoxin Systems as Antibacterial Strategies

4 Sept 2020

Abstract excerpt

The identification of novel targets for antimicrobial agents is crucial for combating infectious diseases caused by evolving bacterial pathogens. Components of bacterial toxin-antitoxin (TA) systems have been recognized as promising therapeutic targets. These widespread genetic modules are usually composed of two genes that encode a toxic protein targeting an essential cellular process and an antitoxin that...

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PMID: 32899634
DOI: 10.3390/toxins12090568

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