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Article

Integrative biology of persister cell formation: molecular circuitry, phenotypic diversification and fitness effects.

Journal of the Royal Society, Interface - 1 Sept 2022

Berkvens Alicia, Chauhan Priyanka, Bruggeman Frank J

Abstract excerpt

Microbial populations often contain persister cells, which reduce the extinction risk upon sudden stresses. Persister cell formation is deeply intertwined with physiology. Due to this complexity, it cannot be satisfactorily understood by focusing only on mechanistic, physiological or evolutionary aspects. In this review, we take an integrative biology perspective to identify common principles of persister cell...

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Identifiers

PMID: 36099930
DOI: 10.1098/rsif.2022.0129
PMCID: PMC9470271

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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