Article
SMAD7 loci contribute to risk of hepatocellular carcinoma and clinicopathologic development among Chinese Han population.
Oncotarget - 19 Apr 2016
Ji Jiansong, Xu Min, Zhao Zhongwei, Tu Jianfei, Gao Jun, Lu Chenying, Song Jingjing, Chen Weiqian, Chen Minjiang, Fan Xiaoxi, Cheng Xingyao, Lan Xilin, Li Jie
Abstract excerpt
Genome-wide association studies (GWAS) have identified three loci at 18q21 (rs4939827, rs7240004, and rs7229639), which maps to SMAD7 loci, were associated with risk of diseases of the digestive system. However, their associations with hepatocellular carcinoma (HCC) risk remain unknown. A case-control study was conducted to assess genetic associations with HCC risk and clinicopathologic development among Chinese...
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