Article
No associations between five polymorphisms in COMT gene and migraine.
Acta neurologica Scandinavica - 1 Feb 2017
Takigawa H, Kowa H, Nakashima K
Abstract excerpt
OBJECTIVES: The pathophysiology of migraine headaches is not clearly understood yet. The dopaminergic system has been hypothesized to be involved in migraine pathogenesis. The aim of this study was to investigate catechol-O-methyltransferase (COMT) polymorphisms and chronic headaches. We analyzed five single nucleotide polymorphisms (SNPs) in COMT. MATERIALS & METHODS: The study population consisted of 71...
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