Article
Catechol-O-methyltransferase (COMT) gene polymorphisms as risk factor in temporomandibular disorders patients from Southern Italy.
The Clinical journal of pain - 1 Feb 2014
Michelotti Ambrosina, Liguori Rosario, Toriello Mario, D'Antò Vincenzo, Vitale Dino, Castaldo Giuseppe, Sacchetti Lucia
Abstract excerpt
OBJECTIVES: To evaluate the role of COMT gene variants as potential risk factors in a group of patients affected with chronic temporomandibular disorder (TMD) pain. METHODS: We sequenced COMT gene in 182 Italian subjects (50 affected by TMD and 132 controls). The study population consisted of patients affected by myogenous and/or arthrogenous pain (RDC/TMD: Ia, Ib, IIIa, IIIb diagnostic categories). RESULTS: We...
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